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Part VIII:

Chronic Conditions & Medications

A photograph of an elderly woman in glasses, in her right hand are numerous pills, her left index finger is pointing to the pills, she is looking down at them in her hand.  There are medication bottles on the table in front of her.

Relevance to Centers for Independent Living (CILs)

As a person ages, they may develop multiple chronic conditions. An older adult's functional status may be affected by a combination of multiple conditions treated by multiple medications. This section covers the common chronic conditions that may affect older adults' (age 60+) functional independence.

Chronic conditions and age-related changes may contribute to declining function and loss of independence. They affect everyday activities such as activities of daily living (ADLs), driving, and employment. CILs that understand the affects of these conditions will be able to provide information and training about assistive technology, self-advocacy, hiring a personal assistant, home modification and transportation to consumers, caregivers, and family members.

Due to the number of chronic conditions and age-related changes that an older consumer may experience, they may also be consuming large quantities (as many as 8 or more) of medications. The older adult who consumes large numbers of medications may have difficulty remembering to take their medications at the designated time, may overdose due to forgetfulness or the large number of medications prescribed, or may forget to take them at all. The effects of medications can have a profound impact on performance. A consumer may appear confused, disoriented or intoxicated because of over-medication, absence of medication or medication reaction.

A list of medications used for treating common chronic conditions and age-related changes is provided with the medications' uses, potential side effects and potential interactions. This information will enable CILs to tell whether the individual is unable to perform daily activities because of decline in physical or cognitive function or because of improper medication administration.

Part VIII: Chronic Condition

Chronic Conditions | Heart Disease and Stroke | Cancer | Chronic Obstructive Pulmonary Disease (COPD) | Falls and Accidents | Diabetes | Pneumonia/Flu | Alzheimer's Disease and Dementia | Kidney Disease | Arthritis

 

Introduction

This section provides CIL personnel with information about the most common chronic conditions that affect the functional status of older adults. Generally, older adults are faced with age-related physical changes and at least one chronic condition. Arthritis is the leading cause of disability in America with heart disease and stroke as the leading causes of death. It is important to understand that these and other chronic conditions have a great impact on independence, safety and quality of life for older adults. These conditions may cause the individual to seek help for assistance in their activities of daily living (ADLs) or instrumental activities of daily living (IADLs). Since 2000, it is known that two out of five people over the age of 70 need help with one or more daily activities. Many older adults rely heavily on family and friends for assistance, while others do not receive the care they need. By 2030, it is estimated that 21 million elderly people may need help with their activities due to functional limitations.

Learning about the impact of the chronic conditions on functional status (causes, symptoms, suggested treatments and medications) will help the older adult understand their disabilities. CILs are suited to assist these elders and their informal caregivers by providing training in assistive technology use, self-advocacy, hiring personal assistance, home modifications, and transportation. Support groups with other older adults may help lessen the fear and stress brought on by the decline of functional status.

What is a chronic condition? A chronic condition is one that is persistent or continuous over an extended period. They can be non-life threatening, such as allergies, or life threatening, such as high blood pressure.1 Currently, there are 125 million people who suffer from chronic conditions. By 2030, it is expected that this number will rise to 171 million. Seventy-seven percent of Medicaid spending is for those community-based persons living with chronic conditions.2

In 2002, the Center for Disease Control (CDC) reported that chronic conditions, which included heart disease, stroke, diabetes, and cancer, were among the most common, costly, and preventable of all health problems. Chronic conditions are the leading causes of disability among adults and cause considerable pain, suffering and poor quality of life for millions of Americans. Medical care costs for people with chronic diseases account for more than 70% of the nation's $1 trillion spent on health care each year.3 The Center for Disease Control reports that two out of seven Americans die of a chronic disease.4

Due to advances in medicine and technologies, people are living longer and having more productive lives. Older people have a much greater risk of suffering from chronic illnesses than younger people. Researchers have reported that life expectancy for women is higher than that for men. Because of this, women age 70+ are more likely to live alone and be disabled for longer periods of time.

The CDC reported that activity limitations are common among elders who have arthritis and other musculoskeletal conditions, heart and other circulatory problems, vision and hearing difficulties, diabetes and respiratory problems. Activity limitations were found to involve managing personal care needs, activities of daily living (i.e. bathing, dressing), and instrumental activities of daily living (i.e. shopping, housekeeping, managing money). Also, the CDC found that these limitations were much more common among the elderly than those in the working-age group (ages 18-44).5 "The prevalence of multiple chronic conditions increases with age. A study by Reed and colleagues found that 37% of working-age Americans had at least one chronic health condition. 7 By age 65 and older, 62% have two or more chronic conditions and by age 80 and older, 70% have five or more chronic conditions.6

On average, those with five or more chronic conditions fill about 50 prescriptions and visit their physicians 15 times per year. Twenty percent of Medicare recipients have five or more chronic conditions.8 According to a research study conducted by Johns Hopkins Bloomberg School of Public Health in November 2002, Medicare recipients age 65 and over with four or more chronic conditions were 99 times more likely to experience one or more hospitalizations that could have been prevented.9

"As people age and experience either age-related changes or functional limitations from chronic health conditions they must learn new ways of interacting within their physical environments to successfully carry out daily life activities."10 The National Academy on an Aging Society reported, "on the whole, the conditions that are most common among older age groups require more care, are more disabling, and are more difficult and costly to treat than the conditions that are more common for younger age groups. For the future, it will be important to find ways to help this growing, aging population live more active and productive lives. It will be equally important to recognize that different groups of chronically ill people will have different needs."11

The U.S. does not have an effective system to care for chronic conditions. The available system of care is fragmented, inappropriate and difficult to obtain.12 One out of three people with chronic conditions do not understand the eligibility requirements for services, how to access the services, or who provides the services.13 Many services essential to caring for the chronically ill and disabled -including supportive care, rehabilitation and prevention of secondary conditions such as bedsores and depression-may be non-medical in nature, provided at home, and require healthcare workers other than physicians and little or low technology.14

Leading Causes of Disability of U. S. Adults, 199919
Bar chart of the Leading Causes of Disability of U.S. Adults, 199915


Engaging in an active lifestyle with good nutrition and exercise can help prevent the onset of these chronic conditions. According to the World Health Organization (WHO), "sedentary lifestyles increase all causes of mortality, double the risk of cardiovascular diseases, diabetes, obesity, and increase the risks of colon cancer, high blood pressure, osteoporosis, lipid disorders, depression and anxiety."15 WHO states physical inactivity can have serious implications for people's health. Approximately two million deaths per year are attributed to physical inactivity, prompting WHO to issue a warning that a sedentary lifestyle could very well be among the 10 leading causes of death and disability in the world. Sixty to eighty-five percent of people in the world-from both developed and developing countries-lead sedentary lifestyles, making it one of the more serious yet insufficiently addressed public health problems of our time. Physical inactivity, along with increasing tobacco use and poor diet and nutrition, are increasingly becoming part of today's lifestyle leading to the rapid rise of diseases such as cardiovascular diseases, diabetes, or obesity. 16

AARP reports the number one fear of older people with disabilities is losing their independence. Chronic conditions can impact the functional ability of older adults. Study participants, age 50+, indicated that at some point they may need assistance with their daily activities and thought their family would help them. But those of lower economic status were found to be at a higher risk. The key components for all people needing assistance include a physical environment and social network that would support them.17 Judy Heumann, co-founder of the World Institute on Disability said, "Independent living is not doing things for yourself, but having the control over how things are done."18

References

1Retrieved on March 1, 2004 from http://www.nlm.nih.gov/medlineplus/ency/article/002312.htm#visualContent

2"The Problem: About Chronic Conditions," Partnership for Solutions, July 24, 2002, Retrieved on March 1, 2004 from www.partnershipforsolutions.org/program

3Retrieved on March 1, 2004 from www.chronicdisease.org/0602-general chronic disease.html

4Retrieved on March 1, 2004 from www.cdc.gov/nccdphp/overview.htm

5Chartbook on Trends in the Health of America, Centers for Disease Control and Prevention, National Center for Health Statistics, DHHS Publication No. 1231-1, August 2002

6"The Problem: About Chronic Conditions," Partnership for Solutions, July 24, 2002. Retrieved on March 1, 2004 from www.partnershipforsolutions.org/program

7Reed, M.C. & Tu H.T., "Triple jeopardy: Low income, chronically ill and uninsured in America" (Issue Brief No. 49), Washington, DC: Center for Studying Health System Change, 2002.

8"Medicare: Cost and Prevalence of Chronic Conditions," Partnership for Solutions, July 2002

9Gitlin, Laura N., "Assistive Technology in the Home and Community for Older People: Psychological and Social Considerations," Assistive Technology: Matching Device and Consumer for Successful Rehabilitation, Scherer, M. J. (ed). 2002.

10Wolff, J. Starfield, B .Anderson, G. (2002). Prevalence, Expenditures, and Complications of Multiple Chronic Conditions in the Elderly, Archives of Internal Medicine. 162:2269-2276.

11"Challenges for the 21st Century: Chronic and Disabling Conditions," National Academy on an Aging Society, Number 1, November, 1999, p.1, 5. www.agingsociety.org

12"Chronic Care in America: A 21st Century Challenge," Robert Wood Johnson Foundation, November 1996, pg. 11. Retrieved on March 1, 2004 from http://www.rwjf.org/publications/publicationsPdfs/Chronic_Care_in_America.pdf

13"Chronic Care in America: A 21st Century Challenge", Robert Wood Johnson Foundation, November 1996, pg. 20. Retrieved on March 1, 2004 from http://www.rwjf.org/publications/publicationsPdfs/Chronic_Care_in_America.pdf

14"Chronic Care in America: A 21st Century Challenge," Robert Wood Johnson Foundation, November 1996, pg. 22. Retrieved on March 1, 2004 from http://www.rwjf.org/publications/publicationsPdfs/Chronic_Care_in_America.pdf

15Prevalence of Disabilities and Associated Health Conditions Among Adults - United States, 1999, MMWR 2001:50(7): 120-5. Retrieved on March 1, 2004 from http://www.cdc.gov/nccdphp/arthritis/index.htm#graph1.

16Physical Inactivity a Leading Cause of Disease and Disability, World Health Organization Press Release, WHO/23, 4 April 2002. Retrieved on March 1, 2004 from http://www.who.int/mediacentre/releases/release23/en/

17American Association of Retired Persons. Retrieved on March 1, 2004 fromhttp://research.aarp.org/il/beyond_50_il.html

18Rehabilitation Research and Training Center or Independent Living Management (2003). Independent Living Philosophy and History. Quote from interview with Judy Heumann.

19Prevalence of Disabilities and Associated Health Conditions Among Adults - US, 1999, MMWR 2001: 50(7): 120-125. Retrieved on March 1, 2004 from http://www.cdc.gov/nccdphp/arthritis/index.htm#graph1

Resources

American Heart Association (AHA) - http://www.americanheart.org
In working to fulfill its mission to reduce disability and death from cardiovascular diseases, the American Heart Association encourages federal, state and local legislators to support public policies that advance the fight against heart disease, stroke and other cardiovascular diseases. This organization provides information to the public about various diseases and conditions that affect the heart, their warning signs, treatment or preventive measures to reduce risk.

American Heart Association
National Center
7272 Greenville Avenue
Dallas, TX 75231
1-800-242-8721 (P)
American Diabetes Association (ADA) - http://www.diabetes.org
The American Diabetes Association is the nation's leading nonprofit health organization providing diabetes research, information and advocacy. The mission of the Association is to prevent and cure diabetes and to improve the lives of all people affected by diabetes.

American Diabetes Association
Attn: National Call Center
1701 North Beauregard Street
Alexandria, VA 22311
1-800-DIABETES (1-800-342-2383) (P)
American Cancer Society (ACS) - http://www.cancer.org
The American Cancer Society is the nationwide community-based voluntary health organization dedicated to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and service. ACS is committed to fighting cancer through balanced programs of research, education, patient service, advocacy, and rehabilitation. Headquartered in Atlanta, Georgia, the ACS has state divisions and more than 3,400 local offices.

American Cancer Society
1599 Clifton Road, NE
Atlanta, GA 30329
Toll: 1-800-227-2345
(404) 320-3333 (P)
(404)329-5787(F)
American Lung Association (ALA) - http://www.lungusa.org
An organization dedicated to the prevention, cure and control of lung diseases such as asthma, emphysema, tuberculosis, and lung cancer. The Association offers community service, public health education, advocacy, and research.

American Lung Association
1740 Broadway
New York, NY 10019-4374
1-800-586-4872 (toll free)
(212) 315-8700 (P)
American Stroke Association (ASA) - http://www.strokeassociation.org
A division of the American Heart Association, ASA provides the Stroke Family Warmline, a toll-free information and referral service offering lists of certified doctors who are stroke specialists, volunteer stroke survivors and family members. Callers receive support and can request free information. ASA publishes Stroke Connection, a priced subscription magazine for survivors and families.

American Stroke Association
National Center
7272 Greenville Avenue
Dallas TX 75231
1-888-4STROKE (478-7653) (P)
Arthritis Foundation - http://www.arthritis.org
A nonprofit, volunteer organization focusing on research and information to cure, prevent, or better treat arthritis and related diseases. Contact the Arthritis Foundation for information on arthritis, related diseases (such as lupus, fibromyalgia and rheumatism), and referrals to local chapters, specialists, or support groups. Publications and videos are available on topics such as self-help and exercise therapy.

Arthritis Foundation (AF)
National Office
1330 West Peachtree Street
Atlanta, GA 30309
1-800-283-7800 (toll free) (P)
(404) 965-7537 (P)
(404) 872-0457 (F)
Bone & Joint Decade (2002-USA-2011) - http://www.boneandjointdecade.org/usa
On January 13, 2000, the Bone and Joint Decade was formally launched at the headquarters of the World Health Organization in Geneva, Switzerland. The Bone and Joint Decade is a global, multi-disciplinary initiative targeting the care of people with musculoskeletal conditions--bone and joint disorders. Its focus is on improving your quality of life as well as advancing the understanding and treatment of those conditions through research, prevention and education. Their site provides information and the latest news, presentations, and research about bone and joint diseases around the world. Supporting organizations of the Bone and Joint Decade are engaged in developing new research and education programs that will bring about significant advances in the knowledge, diagnosis and treatment of musculoskeletal conditions, and increase the number of resources at the disposal of the healthcare profession and the public at large.

United States Bone and Joint Decade, NFP (USBJD)
6300 North River Road
Rosemont, IL 60018
(847) 384-4010 (P)
(847) 823-0536 (F)
Email: usbjd@usbjd.org
HealingWell.com - http://www.HealingWell.com
HealingWell.com is an information resource for patients, caregivers, and families coping with diseases, disorders and chronic illness. It offers health resources and interactive tools to enable patient's to take control of their illness and start the healing process. These include medical news, feature articles, doctor-produced video web casts, message boards and chat rooms, email, web site hosting (yoursite.healingwell.com), health e-greeting cards, newsletters, books and reviews, and resource directories. However, they do not provide medical advice or answer medical related questions.
Medline Plus Health - http://www.medlineplus.gov
This website has health information from the world's largest medical library, the National Library of Medicine. Its information is always up to date. "It has extensive information from the National Institutes of Health and other trusted sources on over 650 diseases and conditions. There are also lists of hospitals and physicians, a medical encyclopedia and a medical dictionary, health information in Spanish, extensive information on prescription and nonprescription drugs, health information from the media, and links to thousands of clinical trials. Medline Plus is updated daily. There is no advertising on this site, nor does Medline Plus endorse any company or product."
National Center for Chronic Disease Prevention and Health Promotion - http://www.cdc.gov/nccdphp
CDC's National Center for Chronic Disease Prevention and Health Promotion is at the forefront of the nation's efforts to prevent and control chronic diseases. The center conducts studies to better understand the causes of these diseases, supports programs to promote healthy behaviors, and monitors the health of the nation through surveys. Critical to the success of these efforts are partnerships with state health and education agencies, voluntary associations, private organizations, and other federal agencies. Information on health topics from A-Z is provided. Recently the CDC posted The Burden of Chronic Diseases and Their Risk Factors: National and State Perspectives 2004 on its website. To access the document, visit http://www.cdc.gov/nccdphp/burdenbook2004/index.htm.
National Center for Injury Prevention and Control of the Centers for Disease Control and Prevention - http://www.cdc.gov/ncipc
The National Center for Injury Prevention and Control (NCIPC) works to reduce morbidity, disability, mortality, and costs associated with injuries. Its website provides information about injury care, violence, unintentional injuries, and resources and health topics from A-Z.

National Center for Injury Prevention and Control
Mailstop K65
4770 Buford Highway NE
Atlanta, GA 30341-3724
(770) 488.1506 (P)
(770) 488.1667 (F)
Email: OHCINFO@cdc.gov
National Diabetes Information Clearinghouse - http://www.niddk.nih.gov
The National Diabetes Information Clearinghouse is funded by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health. The Clearinghouse provides referrals to diabetes specialists and organizations and searches from its database of patient and professional educational materials. Publications are available upon request on topics such as alternative therapies, controlling diabetes, complications of diabetes, and diabetes in Asian, Hispanic, and other ethnic groups.

National Diabetes Information Clearinghouse
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
1 Information Way
Bethesda, MD 20892-3560
1-800-860-8747 (P)
(301) 654-3327 (P)
(301) 907-8906(F)
National Health Council - http://www.nhcouncil.org
The council and its member organizations share a common objective: improving the health of all people, particularly those with chronic diseases and/or disabilities. It's mission is to promote the health of all people by advancing the voluntary health movement. Volunteers drive the movement by working together toward prevention, treatment, and cure of diseases and disability.

National Health Council
1730 M. Street, NW, Suite 500
Washington, D.C. 20036-4505
(202) 785-3910 (P)
(202) 785-5923 (F)
Email: info@nhcouncil.org
National Health Information Center (NHIC) - http://www.health.gov/nhic
This information center is a service of the federal government, links consumers and health professionals with resources and information. The Center provides health information, contacts for federally supported health information centers, lists of national health observances, and toll-free numbers sponsored by the federal government.

National Health Information Center
Office of Disease Prevention and Health Promotion
Department of Health and Human Services
P.O. Box 1133
Washington, DC 20013-1133
(800) 336-4797) (P)
(301) 565-4167 (P)
(301) 984-4256 (F)
National Osteoporosis Foundation - http://www.nof.org
The National Osteoporosis Foundation is a nonprofit, voluntary health organization dedicated to promoting lifelong bone health to reduce the widespread prevalence of osteoporosis and related fractures. It works to find a cure for osteoporosis through research, education, and advocacy. The Foundation provides general information on osteoporosis through its quarterly newsletter and booklets.

National Osteoporosis Foundation
1232 22nd Street, NW
Washington, DC 20037-1292
(202) 223-2226 (P)
(202)223-2237 (F)
National Multiple Sclerosis Society - http://www.nmss.org
The mission of the National Multiple Sclerosis Society is to end the devastating effects of MS. It provides accurate, up-to-date information to persons with MS, their families, and healthcare providers. The Society and its network of chapters nationwide promote research, educate, advocate on critical issues, and organize a wide range of programs.

The National Multiple Sclerosis Society
733 Third Avenue
New York, NY 10017
1-800-FIGHT MS (P)
(Check their website for your local chapter's mailing address and number)
Robert Wood Johnson Foundation (RWJF): http://www.rwjf.org/index.jsp
The Robert Wood Johnson Foundation seeks to improve the health and health care of all Americans. Two of the areas they focus on in grant-making are: to improve the quality of care and support for people with chronic health conditions and to promote healthy communities and lifestyles. Grantees are as varied as the challenges they tackle. They include: hospitals, medical, nursing, and public schools, hospices, professional associations, research organizations, state and local government agencies, and community groups.

The RWJF has made eight awards as part of its Community Partnerships for Older Adults Program. The grantees received an average of $750,000. The purpose is to promote collaboration between local agencies in helping older people at risk of being disabled due to low-economic status, race or ethnicity, chronic illness or advanced age. For more information, contact RWJF at (609) 627-5937 or www.partnershipsforolderadults.org.
SafetyLit (Injury Prevention Literature Update) - http://www.safetylit.org
SafetyLit provides information about the occurrence and prevention of injuries that is available from many sources and disciplines. SafetyLit staff and volunteers regularly examine more than 300 journals and scores of reports from government agencies and organizations. The weekly update is posted before 6 a.m. GMT every Monday morning. They provide a free email announcement of the titles, authors, and publishers of the abstracts included in each weekly update. An online form is available for those who would like to subscribe to this service.

SafetyLit
6505 Alvarado Road, Suite 208
San Diego, CA 92120, USA
(619) 594-3691 (P)
(619) 594-1995 (F)
United Seniors Health Cooperative - http://www.unitedseniorshealth.org
The United Seniors Health Cooperative is a nonprofit organization dedicated to helping older consumers, caregivers, and professionals. The Council produces publications on topics such as financial planning, managed care, and long-term care insurance.

United Seniors Health Cooperative
409 3rd Street, NW, Suite 200
Washington, DC 20024
1-800-637-2604 (toll free)
(202) 479-6973 (P)
(202) 479-6660 (F)
World Health Organization - http://www.who.int.en
The World Health Organization (WHO), the United Nations specialized agency for health, was established on April 7,1948. WHO's objective, as set out in its constitution, is the attainment by all peoples of the highest possible level of health. Health is defined in WHO's Constitution as a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.

It's website provides information about each country that is a member of WHO, WHO projects, initiatives, activities, information products, and contacts, organized by health and development topics, online book shop, WHO's library database, and other links to information about health, disease, aging, etc.

Medication Resources

WebMD

WebMD provides drug information gathered from databases provided by Multum Information Services, Inc. The types of information available about medications include: a description of the medication and its appearance, a description of who should not take it, possible side effects, use of the medication, topics to discuss with a doctor before taking the medication, how the medication should be taken, what to do if a dose is missed, symptoms of an overdose, what to avoid when taking the medication, other medications that may interact with the medication, and brand names of the medication.

To use WebMD for medication information go to http://www.webmd.com/ and click on WebMD Health. Under Medical Info, click on drugs and herbs. Under look up drugs and supplements, click on start here. The user must agree to the conditions of use and then may search for a particular medication by typing the name or clicking on the letter the medication starts with and choosing it from a list presented.

PDR Health

The information provided at this site is written in easy to understand terms and is based on the FDA approved information that is available in the Physician's Desk Reference. The types of information available about medications include: use of the medication, important facts about the drug, how the medication should be taken, potential side effects, warnings/ precautions, possible food and drug interactions with the medication of interest, recommended dosage, overdose symptoms, and the appearance of the medication.

To use PDR Health, go to http://www.gettingwell.com/ and click on drug information. Then you can either type in the name of the drug or click on the type of drug (prescription, over-the-counter, herbal, or a supplement). After clicking the type of drug, click on the letter the drug begins with and its name.

Medline Plus

This website is sponsored by the U.S. National Library of Medicine and the National Institutes of Health. It contains information on medications and contains a medical encyclopedia and dictionary. The site utilizes MedMaster from the American Society of Health-System Pharmacists (ASHP) and the USP DI Advice for the Patient from the United States Pharmacopeia (USP) to provide information on prescription and over-the-counter medications. The type of information available on medications includes: brand names in the U.S. and Canada, use for the medication, available forms of the medication (liquid, capsules, tablet), precautions, warnings, proper use and dosing of the medication, what to do if a dose is missed, storage of the medication, potential side effects, and precautions while using the medication.

To use Medline Plus, go to http://www.nlm.nih.gov/medlineplus/druginformation.html and click on the first letter of the medication. Then locate the name of the medication in the list and click on either MedMaster or USP DI below the name to view information.

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Part VIII: Chronic Conditions & Medications


Section A: Heart Disease and Stroke

The leading cause of death of Americans is heart disease. Heart disease is a type of cardiovascular disease that includes various heart conditions, such as high blood pressure and stroke. Stroke is the third leading cause of death. According to the American Heart Association, approximately half of stroke deaths occur before the person reaches the hospital.1 Heart disease and stroke involves the heart and its arteries.

Coronary heart disease is a result of the narrowing of the heart arteries, which can decrease the blood and oxygen supply to the heart. This leads to a heart attack or chest pain. A heart attack occurs when there is a sudden blockage to the coronary artery, usually by a blood clot. If cholesterol and fatty deposits build up in the heart's arteries, less blood reaches the heart muscle. This damages the heart muscle, and the healthy heart tissue that remains has to work harder. The person experiences chest pain when the heart does not receive enough blood. According to the CDC, "two of the major independent risk factors for cardiovascular disease are high blood pressure and high blood cholesterol. About 90% of middle-aged Americans will develop high blood pressure in their lifetime, and nearly 70% of people with high blood pressure do not have it under control."2

Another type of heart disease is a heart rhythm disorder commonly known as arrhythmias. It is due to an interference of the regular beating rhythm of the heart. This includes disorganized, disrupted and fast beating of the heart, heart murmurs and other undetermined disorders. Two-million Americans live with atrial fibrillation with little consequence while in others it can lead to heart disease, stroke or heart attack.3

Congestive heart failure (CHF) is also a type of heart disease. It is often considered the end-stage of heart disease. It is a condition where the heart cannot pump enough blood to the body's other organs.4 Uncontrolled blood pressure doubles a person's risk of developing heart failure. When pressure within the blood vessels is too high, the heart has to pump harder than normal to keep the blood circulating. This takes a toll on the heart, and over time the heart chambers become larger and weaker. When performing daily activities, the individual with CHF will fatigue easily and experience shortness of breath.

Nearly 5 million Americans are living with heart failure with 550,000 new cases diagnosed each year. Although more than half of the population with heart disease is under the age of 65, the elderly are affected to a much greater extent.5 The elderly are more likely to experience heart attacks and chest pains. The prevalence of heart disease is greater in older men, males of African-American descent, those from lower economic status, and people who have less than a high school education.

A stroke occurs when a blood vessel carrying oxygen and nutrients to the brain is blocked or bursts. When that happens, part of the brain cannot get the blood and oxygen it needs and starts to die. As part of the brain dies from the lack of blood flow, it affects the part of the body controlled by the dying portion of the brain. Strokes can cause paralysis, affect language and vision, and cause various other problems. One side of the brain controls the opposite side of the body. For example, if the stroke occurs in the brain's right side, the left side of the body (and the right side of the face) will be affected, which could produce any or all of the following:6

• Paralysis on the left side of the body

• Vision problems

• Impulsive, inquisitive behavioral style

• Memory loss

If the stroke occurs in the left side of the brain, the right side of the body (and the left side of the face) will be affected, producing some or all of the following:

• Paralysis on the right side of the body

• Speech/language problems (slurred speech, word finding problems)

• Slow, cautious behavioral style

• Memory loss

Elders diagnosed with heart disease and stroke are more likely to have difficulties with every day activities. These activities include self-care (i.e. bathing, dressing, eating, and toileting), mobility skills (i.e. use of toilet, walking, getting in and out of bed), and other skills (i.e. communication, vision, memory). Those with heart disease spend five or more days in bed due to fatigue and shortness of breath.

High blood pressure, diabetes, smoking and a sedentary lifestyle are contributing factors to heart disease and stroke. "Although many cardiovascular diseases (CVDs) can be treated or prevented, an estimated 17 million people die of CVDs each year. A substantial number of these deaths can be attributed to tobacco smoking, which increases the risk of dying from coronary heart disease and cerebrovascular disease 2-3 fold. The risk increases with age and is greater for women than for men. In contrast, cardiac events fall 50% in people who stop smoking and the risk of CVDs, including acute myocardial infarction, stroke and peripheral vascular disease, also decreases significantly over the first two years after smoking cessation."7

Blood pressure classification for adults age 18 and older

Blood Pressure Category

Systolic (mmHg)

 

Diastolic (mmHg)

Normal*

Less than 120

And

Less than 80

Pre-hypertension

120 -139

Or

80 - 89

Hypertension, Stage 1

140 - 159

Or

90 - 99

Hypertension, Stage 2

160 - higher

Or

100 - higher

*Unusually low readings should be evaluated for clinical significance, chart available, see reference #8.8

Hypertension usually affects people later in life, age 55 and over. Blacks and elderly women are more susceptible to developing hypertension. Those with hypertension are reported to be more ill with chronic conditions and use more health care services than those without hypertension.

References

1American Heart Association. Heart and Stroke Statistics 2003 Update. Available at www.americanheart.org

2National Center for Chronic Disease Prevention and Health Promotion. Available at http://www.cdc.gov/nccdphp/aag/aag_cvd.htm

3Cleveland Clinic Heart Center. Available at http://www.clevelandclinic.org/heartcenter/pub/atrial_fibrillation

4American Heart Association. Available at www.americanheart.org

5Heart and Stroke Facts Booklet, pg.13 & 41, American Heart Association. Available at http://www.americanheart.org/downloadable/heart/1056719919740HSFacts2003text.pdf

6National Stroke Association. Available at www.strokeassociation.org

7Dr. Derek Yach, Executive Director, Non-Communicable Diseases and Mental Health Cluster, CVD Prevention and Control: Missed opportunities, World Health Organization.

8Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7 Express) NIH Publication No. 03-5233, May 2003.

Resources

American Heart Association - http://www.americanheart.org
Their mission is to reduce disability and death from cardiovascular diseases and stroke. Literature is available for the consumer, caregivers and health professionals about these diseases.

American Heart Association
National Center
7272 Greenville Avenue
Dallas, TX 75231
American Stroke Association -www.strokeassociation.org

American Stroke Association
National Center
7272 Greenville Avenue
Dallas, TX 75231

Heart and High Blood Pressure Medications

Nitroglycerin/ Nitrogard/ Nitrostat

Uses: For relief of chest pain due to coronary artery disease.

Potential side effects: Vertigo, dizziness, weakness, palpitation, headache, nausea, vomiting, weakness, sweating, fainting, flushing, rash

Medications that may interact: High blood pressure medications, beta-adrenergic blockers, phenothiazines, calcium channel blockers, alcohol, aspirin, alteplase, ergotamine, heparin, dihydroergotamine, viagra

Adalat/ Procardia (Nifedipine)

Uses: Relieves chest pain and used for high blood pressure

Potential side effects: Edema, headache, flushing, dizziness

Medications that may interact: Alfuzosin, grapefruit juice, digoxin, cimetidine

Propranolol/ Inderal

Uses: A beta-blocker, for the treatment of high blood pressure, chest pain, irregular heart beats; helps prevent migraines; and relieves severe tremors

Potential side effects: Decreased sexual ability, drowsiness, trouble sleeping, tiredness, weakness, slow heart beat, dizziness, difficulty breathing, swelling, depression, cold hands and feet

Medications that may interact: Reserpine, calcium-channel-blocking drug, haloperidol, aluminum hydroxide gel, alcohol, phenytoin, phenobarbitone, rifampin, chlorpromazine, antipyrine, lidocaine, thyroxine, cimetidine, theophylline

Isosorbide mononitrate/ Ismo/ Imdur/ Monoket

Uses: To treat long-term chest pain associated with coronary artery disease.

Potential side effects: Headache, dizziness

Medications that may interact: Other vasodilators, calcium channel blockers, alcohol

Vasotec (Enalapril, Enalaprilat, ACE inhibitor)

Uses: Used for high blood pressure and congestive heart failure

Potential side effects: Hypotension, dizziness

Medications that may interact: Diuretics, non-steroidal anti-inflammatory drugs, lithium, potassium salts

Digoxin (Digitalis, Lanoxin)

Uses: Congestive heart failure and irregular heart rhythms (atrial fibrillation)

Potential side effects: Anorexia, nausea, diarrhea, vomiting, blurred or yellow vision, headache, weakness, dizziness, apathy, confusion, anxiety, depression, delirium, and hallucination.

Medications that may interact: Diuretics, calcium, quinidine, verapamil, amiodarone, propafenone, indomethacin, itraconazole, alprazolam, spironolactone, erythromycin, clarithromycin, tetracycline, propantheline, diphenoxylate, antacids, kaolin-pectin, sulfasalazine, neomycin, cholestyramine, certain anticancer drugs, metoclopramide, and Rifampin

Pravastatin/ Pravachol

Uses: To lower blood cholesterol on those at risk of stroke or heart disease

Potential side effects: Headache

Medications that may interact: Erythromycin, cyclosporine, niacin, fibrates, cholestyramine, colestipol, gemfibrozil

Verapamil/ Calan SR/ Covera-HS/ Isoptin SR, Verelan

Uses: A calcium channel blocker, for the treatment of high blood pressure

Potential side effects: Constipation

Medications that may interact: Alcohol, cyclophosphamide, oncovin, procarbazine, prednisone, vindesine, adriamycin, cisplatin, doxorubicin, aspirin, beta-blockers, digitalis, vasodilators, angiotensin-converting enzyme inhibitors, diuretics, prazosin, disopyramide, flecainide, quinidine, lithium, carbamazepine, rifampin, phenobarbital, cyclosporine, theophylline

Digoxin (Digitalis, Lanoxin)

Uses: Congestive heart failure and irregular heart rhythms (atrial fibrillation)

Potential side effects: Anorexia, nausea, diarrhea, vomiting, blurred or yellow vision, headache, weakness, dizziness, apathy, confusion, anxiety, depression, delirium, and hallucination.

Medications that may interact: Diuretics, calcium, quinidine, verapamil, amiodarone, propafenone, indomethacin, itraconazole, alprazolam, spironolactone, erythromycin, clarithromycin, tetracycline, propantheline, diphenoxylate, antacids, kaolin-pectin, sulfasalazine, neomycin, cholestyramine, certain anticancer drugs, metoclopramide, and Rifampin

Cardizem (Diltiazem)

Uses: Relieves chest pain and used for high blood pressure

Potential side effects: Headache, dizziness

Medications that may interact: Beta-blockers, cimetidine, digoxin, anesthetics, carbamazepine, alfuzosin, astemizole, cisapride, grapefruit juice, pimozide, and terfenadine

Adalat/ Procardia (Nifedipine)

Uses: Relieves chest pain and used for high blood pressure

Potential side effects: Edema, headache, flushing, dizziness

Medications that may interact: Alfuzosin, grapefruit juice, digoxin, cimetidine

Toprol XL / Lopressor(Metoprolol succinate, beta-blocker)

Uses: Relieves chest pain and used for high blood pressure, heart failure

Potential side effects: Tiredness and dizziness, depression, mental confusion, bradycardia, shortness of breath, diarrhea, rash

Medications that may interact: Reserpine, monoamine oxidase (MAO) inhibitors, quinidine, fluoxetine, paroxetine, propafenone, and clonidine

Note: this medication should not be stopped abruptly

Vasotec ( Enalapril, Enalaprilat, ACE inhibitor)

Uses: Used for high blood pressure and congestive heart failure

Potential Side Efftects: Hypotension, dizziness

Medications that may interact: Diuretics, non-steroidal anti-inflammatory drugs, lithium, potassium salts

Catapres TTS (patch), Clonidine skin patch

Uses: Used for high blood pressure

Potential side effects: Dry mouth, drowsiness, fatigue, headache, lethargy, sedation, localized skin reactions and rashes, fever, and pallor

Medications that may interact: Alcohol, barbiturates or other sedating drugs, tricyclic antidepressants, digitalis, calcium channel blockers and beta-blockers, amitriptyline

Dynacric (Isradipine, calcium channel blocker)

Uses: Used for high blood pressure

Potential side effects: Dizziness, edema, palpitations, flushing, tachycardia, headache, edema, dizziness, palpitations, and gastrointestinal disturbances

Medications that may interact: Cimetidine, rifampicin, fentanyl anesthesia, alfuzosin, grape fruit juice

Accupril (Quinapril hydrochloride, ACE inhibitor)

Uses: Used for high blood pressure and heart failure

Potential side effects: Dizziness, fatigue, coughing, hypotension

Medications that may interact: Diuretics, potassium salts, tetracycline, lithium

Atenolol (Tenormin, beta-blocker)

Uses: Used for high blood pressure, relieving chest pain, and to prevent migraines

Potential side effects: Dizziness, nausea, bradycardia, hypotension

Medications that may interact: Verapamil, diltiazem, reserpine, calcium channel blockers, clonidine, and indomethacin

Note: this medication should not be stopped abruptly

Norvasc (Amlodipine, calcium channel blocker)

Uses: Used for high blood pressure and to relieve chest pain

Potential side effects: Headache, edema

Medications that may interact: Alfuzosin

Dyazide (Maxide, hydrochlorothiazide/ triamterene, a diuretic)

Uses: Used to treat water retention, swelling, high blood pressure

Potential side effects: Dizziness, headache, fatigue, weakness, nausea, vomiting, diarrhea, constipation, increased hunger or thirst, increased urination, swelling, sun sensitivity

Medications that may interact: Potassium salts, chlorpropamide, indomethacin, anti-inflammatory drugs, lithium, methenamine

Zestril (Lisinopril, Prinivil, ACE inhibitor)

Uses: Used for high blood pressure and heart failure

Potential side effects: Cough, headache, dizziness, fatigue, asthenia, hypotension

Medications that may interact: Diuretics, indomethacin, potassium salts, lithium

Lipitor (Atorvastatin)

Uses: Used to lower cholesterol

Potential side effects: Constipation, flatulence, dyspepsia, and abdominal pain

Medications that may interact: Cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals, and digoxin

Furosemide/ Lasix

Uses: Used for high blood pressure, swelling

Potential side effects: Dry mouth, increased thirst, headache, dizziness, constipation, rash, jaundice, sun sensitivity, and nausea

Medications that may interact: Aminoglycoside antibiotics, ethacrynic acid, salicylates, tubocurarine, succinylcholine, lithium, sucralfate, indomethacin, and anti-inflammatory drugs

Isosorbide mononitrate (Ismo, Imdur, Monoket)

Uses: Used for coronary artery disease and related chest pain

Potential side effects: Headache, dizziness

Medications that may interact: Calcium channel blockers, organic nitrates, and alcohol

Aldomet (Methyldopa)

Uses: Used for high blood pressure

Potential side effects: Sedation, headache, asthenia, and weakness

Medications that may interact: Other anti-hypertensive drugs, anesthetics, lithium, ferrous sulfate, ferrous gluconate, and monoamine oxidase (MAO) inhibitors

Blood Thinners

Aspirin/ Ascriptin/ Bayer/ Ecotrin/ Empirin/ Zorprin/

Uses: Relieves mild to moderate pain, used to thin blood to reduce the risk of heart attack or stroke

Potential side effects: Stomach pain, stomach ulcer, diarrhea, constipation, nausea, vomiting, gas, heartburn

Medications that may interact: Alcohol, alendronate, antacids, anti-inflammatory medications, prednisone, cortisone, other blood thinners, diabetes medications, gout medications, methotrexate, Pepto-Bismol, medications for seizures

Coumadin/ Warfarin

Uses: Prevents and treats blood clots

Potential side effects: Hemorrhage, paralysis, numbness, tingling, pain, dizziness, shortness of breath, swelling, weakness, low blood pressure, purple toes syndrome, hepatitis, jaundice, fever, rash, abdominal pain, fatigue, nausea, vomiting, diarrhea, headache, hair thinning, cold intolerance

Medications that may interact: Other blood thinners, cholesterol medications, alcohol, allopurinol, amiodarone, antibiotics, anti-inflammatory medications, aprepitant, acetaminophen, azathioprine, barbiturates, bosentan, cimetidine, cyclosporine, disulfiram, female hormones, fish oil supplements, influenza virus vaccine, male hormones, cancer medications, heart rhythm medications, blood pressure medications, quinidine, quinine, seizure medications, thyroid medications, tolterodine, vitamin K

Plavix/ Clopidogrel

Uses: To prevent future stroke or heart attack with people who have already experienced a stroke or heart attack

Potential side effects: Chest pain dizziness, hemorrhage, bruising, rash

Medications that may interact: Anti-inflammatory medications, warfarin, phenytoin, tamoxifen, tolbutamide, torsemide, fluvastatin

Heparin

Uses: Prevents blood clots and keeps existing clots from getting bigger

Potential side effects: Hemorrhage, local irritation at injection site, chills, fever, rash, decreased number of platelets, osteoporosis, hair thinning

Medications that may interact: Warfarin, dicumarol, acetylsalicylic acid, dextran, phenylbutazone, ibuprofen, indomethacin, dipyridamole, hydroxychloroquine, digitalis, tetracyclines, nicotine, antihistamines

Diuretics

Dyazide (Hydrochlorothiazide, Triamterene, Maxide)

Uses: Used to treat water retention, swelling, high blood pressure

Potential side effects: Dizziness, headache, fatigue, weakness, nausea, vomiting, diarrhea, constipation, increased hunger or thirst, increased urination, swelling, sun sensitivity

Medications that may interact: Potassium salts, chlorpropamide, indomethacin, anti-inflammatory drugs, lithium, methenamine

Furosemide/ Lasix

Uses: For high blood pressure, swelling

Potential side effects: Dry mouth, increased thirst, headache, dizziness, constipation, rash, jaundice, sun sensitivity, and nausea

Medications that may interact: Aminoglycoside antibiotics, ethacrynic acid, salicylates, tubocurarine, succinylcholine, lithium, sucralfate, indomethacin, and anti-inflammatory drugs

Demadex (Torsemide)

Uses: For high blood pressure and swelling

Potential side effects: Dizziness, headache, nausea, weakness, vomiting, hyperglycemia, excessive urination, hyperuricemia, hypokalemia, excessive thirst, hypovolemia, impotence, esophageal hemorrhage, and dyspepsia

Medications that may interact: Salicylates, nonsteroidal anti-inflammatory agents, indomethacin, cholestyramine, probenecid, lithium, aminoglycoside antibiotics, ethacrynic acid

Hydrochlorothiazide (HydroDIURIL, Esidrix, Oretic)

Uses: For high blood pressure and swelling

Potential side effects: Weakness, hypotension, pancreatitis, jaundice, diarrhea, vomiting, cramping, constipation, gastric irritation, nausea, anorexia, anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia, anaphylactic reactions, angina, respiratory problems, sun sensitivity, fever, rash, electrolyte imbalance, hyperglycemia, glycosuria, hyperuricemia, muscle spasm, vertigo, paresthesias, dizziness, headache, restlessness

Medications that may interact: Alcohol, barbiturates, or narcotics, antidiabetic drugs, other antihypertensive drugs, cholestyramine and colestipol, corticosteroids, norepinephrine, tubocurarine, lithium, non-steroidal anti-inflammatory

Zaroxoyln (Metolazone, Mykrox)

Uses: For high blood pressure and swelling from congestive heart failure and kidney disease

Potential side effects: Chest pain, orthostatic hypotension, depression, dizziness, drowsiness, weakness, restlessness, rashes, vomiting, nausea, diarrhea, constipation, anorexia, muscle cramps

Medications that may interact: Furosemide, other antihypertensive drugs, alcohol, barbiturates, narcotics, digitalis, corticosteroids, lithium, tubocurarine, salicylates, other non-steroidal anti-inflammatory medications, anticoagulants

Triamterene ( Dyrenium)

Uses: For high blood pressure and swelling resulting from heart, kidney, and liver disease

Potential side effects: Anaphylaxis, rash, sun sensitivity, hyperkalemia, hypokalemia, nausea, vomiting, diarrhea, weakness, fatigue, dizziness, headache, dry mouth

Medications that may interact: Lithium, indomethacin, nonsteroidal anti-inflammatory agents, antihypertensive medication, other diuretics, anesthetics, muscle relaxants, low-salt milk, potassium-containing medications, salt substitutes, chlorpropamide, hypoglycemic agents

Electrolyte Replacement

Klor-Con/ Potassium salts (chloride)/ K-Norm/ K-Dur/ Slow-K/ Micro-K/ Klotrix

Uses: For potassium deficiencies, which affect normal functioning of the heart, muscle, and nerves

Potential side effects: Upper and lower gastrointestinal problems and discomfort, too much potassium in blood, nausea, vomiting, gas, diarrhea

Medications that may interact: Anti-inflammatory medications, cisplatin, digoxin, heparin, blood pressure medications, medications for movement disorders, medications for digestive system problems, penicillin G, sodium polystyrene sulfonate, diuretics

Phosphorus Salts/ K-Phos/ Neutra-phos

Uses: To prevent kidney stones

Potential side effects: Dizziness, diarrhea, confusion, high blood pressure, headache, increased thirst, muscle cramps, swelling, nausea, vomiting, rectal burning, stomach cramps

Medications that may interact: Antacids, corticosteroids, corticotrophin, cyclosporine, estrogens, digoxin, digitoxin, heparin, iron supplements, blood pressure medications, pain medications, potassium supplements, sucralfate, testosterone, vitamin D supplements, zinc supplements

Augmentin/ Amoxicillin/ Clavulanic acid/ Clavulanate potassium

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Part VIII: Chronic Conditions & Medications


Section B: Cancer

Cancer is a family of diseases caused by the uncontrolled growth of abnormal cells in a part of the body. The uncontrolled growth spreads beyond the original site. The type of cancer is named from the site of origin. According to the U.S. National Center for Health Statistics' National Vital Statistics Report (2002), cancer is the second leading cause of death in the United States. It is responsible for one of every four deaths in the United States. The number of cancer cases is expected to increase as the aging population increases. According to Georgetown University, "cancer is caused by both external factors (tobacco, chemicals, radiation, and infectious organisms) and internal factors (inherited mutations, hormones, immune conditions and mutations that occur from metabolism)."1

Lung cancer is the most common and deadly form. It is very difficult to detect early and treat. Tobacco and alcohol use increases the risk of getting lung or oral cancer. The more a person consumes alcohol, the higher the person's risk. Combining tobacco with alcohol drives the risk even higher. About 87% of lung cancer deaths are caused by smoking.2 Based on data collected from 1995 to 1999, the CDC estimated that adult male smokers lost an average of 13.2 years of life and female smokers lost 14.5 years of life because of smoking.3

442,398 U.S. Deaths Attributable Each Year to Cigarette Smoking*
pie chart

*Average annual number of deaths, 1995-1999.
Source: CDC. Annual smoking-attributable mortality, years of potential life lost, and economic costs-United States-1995-1999. MMWR 2002; 51(14):300-3.

Stopping tobacco use, or not starting, is the single most important thing a person can do to avoid cancer and other chronic conditions.

In 2002, the Center on Aging Society reported the most common cancer types by gender were: breast, prostate, uterine, cervical and colorectal. Occurrence of cancer increases with age with men having a higher risk of developing cancer than women. African-Americans have a higher incidence of cancer and are about one-third more likely to die from it than whites.4

According to the American Cancer Society, some people are at a greater risk of developing cancer due to hereditary factors. For example, a woman with a mother or sister who has had breast cancer or an individual with a relative who has had colon cancer is at higher risk.

To learn more about specific types of cancer and treatment such as: lung, prostate, cervical, go to the American Cancer Society's website: www.cancer.org.

References

1Center on an Aging Society, Georgetown University, "Cancer: A major national concern," Data Profile, Number,1 July 2002. Available at http://ihcrp.georgetown.edu/agingsociety/pubhtml/cancer/cancer.html

2American Cancer Society, http://www.cancer.org

3Centers for Disease Control, Annual smoking-attributable mortality, years of potential life lost, and economic costs-United States-1995-1999. MMWR 2002; 51(14):300-3.

4Center on an Aging Society, Georgetown University, "Cancer: A major national concern," Data Profile, Number,¹ July 2002. Available at http://ihcrp.georgetown.edu/agingsociety/pubhtml/cancer/cancer.html

Resources

American Cancer Association - http://www.cancer.org

American Cancer Association
1599 Clifton Road, NE
Atlanta, GA 30329
Toll: 1-800- 227-2345

Cancer Medications

Tamoxifen / Nolvadex

Uses: For breast cancer

Potential side effects: Hot flushes, swelling, vaginal discharge, endometrial changes (hyperplasia and polyps), endometriosis, uterine fibroids, ovarian cysts, weight loss, fatigue, cough, hair thinning dizziness, lightheadedness, headache, depression, nausea, anorexia, abdominal cramps, eye changes, visual disturbances, muscle pain, bone pain. Increased risk of uterine cancer, pulmonary embolism, deep-vein thrombosis, stroke

Medications that may interact: Warfarin, Phenobarbital, bromocriptine, cytotoxic drugs, cyclophosphamide

Cysplatin

Uses: Used in combination with other drugs to treat many types of cancer, including: testicular, ovarian, bladder, head, neck, cervical, lung, advanced malignant pleural mesothelioma, esophageal, melanoma, brain

Potential side effects: Bone marrow suppression, low platelet count, low white blood cell count, renal impairment, electrolyte disturbances, nausea, vomiting, anorexia, ear ringing, hearing loss, tingling or loss of sensation in hands and feet, gait difficulties, weakness, seizures, slurred speech, loss of taste, memory loss, tremor, cortical blindness, aphasia, seizures, anemia, facial swelling, flushing, wheezing, difficulty breathing, rapid heart rate, low blood pressure, sweating, stuffy nose, runny nose, conjunctivitis, generalized redness, tight chest, high blood pressure, postural hypotension, mild hair thinning, fatigue, hiccups, muscular pain, fever

Medications that may interact: Amphoteracin, amikacin, gentamicin, neomycin, streptomycin, tobramycin, digoxin, furosemide, torsemide, ethacrynic acid, bumetanide, dofetilide, dypiridamole, warfarin, coumadin, mesna, methotrexate, other chemotherapy agents, probenecid

Proscar/ Propecia (Finasteride)

Uses: Treatment of enlarged prostate, also for hair loss

Potential side effects: Breast enlargement or tenderness, dizziness, diarrhea, painful urination, skin rash, sexual difficulties, stomach pain

Medications that may interact: Blood pressure medications, testosterone

Cyclophosphamide/ Cytoxan

Uses: A chemotherapy that treats many types of cancer, also to treat diseases related to immune system

Potential side effects: Missed menstrual periods, decreased white blood cell count, infection, fast heart rate, fever, chills, shortness of breath, dizziness, confusion, agitation, tiredness, weakness, joint pain, low back pain, painful urination, anemia, loss of appetite, nausea, vomiting, darkening of skin and fingernails, diarrhea, stomach pain, flushing, headache, sweating, rash, hair loss

Medications that may interact: Allopurinol, colchicines, probenecid, sulfinpyrazone, anti-coagulants, bone marrow depressants, radiation therapy, cocaine, cytarabine, daunorubicin, doxorubicin, hepatic enzyme inducers, azathioprine, chlorambucil, corticosteroids, glucocorticoid, cyclosporine, mercaptopurine, muromonab-CD3, lovastatin, succinylcholine, vaccines with killed virus, vaccines with live virus

Prostate Medications

Proscare / Propecia / Finasteride

Uses: Used to reduce size of prostate gland and to treat some male hair loss

Potential side effects: Breast enlargement or tenderness, dizziness, diarrhea, painful urination, skin rash, sexual difficulties, stomach pain

Medications that may interact: Blood pressure medications, testosterone

Terazosin/ Hytrin

Uses: For high blood pressure and prostate problems

Potential side effects: Weakness, postural hypotension, impotence, blurred vision, dizziness, nasal congestion, nausea, swelling, palpitations, drowsiness

Medications that may interact: High blood pressure medications, diuretics

Gastrointestinal Tract Medications

Docusate/ Dulcolax/ Colace/ Surfak

Uses: Laxative and stool softener

Potential side effects: Diarrhea, rash, throat irritation, stomach cramps

Medications that may interact: Mineral oil

Relafen/ Nabumetone (anti-inflammatory medication)

Uses: Relieves pain and inflammation from arthritis

Potential side effects: Diarrhea, heartburn, abdominal pain, constipation, gas, nausea, dizziness, headache, rash, swelling, ear ringing

Medications that may interact: Warfarin

Pepcid / Famotidine/ Mylanta/ Zantac/ Axid

Uses: For treatment of heartburn and stomach ulcers

Potential side effects: Headache, dizziness, constipation, and diarrhea

Medications that may interact: No drug interactions have been found

Prevacid/ Lansoprazole

Uses: Prevents acid production in stomach, helps to relieve symptoms and injury from acid reflux and stomach ulcers

Potential side effects: Abdominal pain, diarrhea, constipation, nausea

Medications that may interact: Theophylline, sucralfate, ketoconazole, ampicillin esters, iron salts, digoxin

Compazine/ Prochlorperazine

Uses: For nausea, vomiting, schizophrenia, anxiety

Potential side effects: Drowsiness, dizziness, blurred vision, skin reactions, low blood pressure, jaundice, decreased white blood cell count, agitation, insomnia, muscle spasms, tongue protrusion, difficulty swallowing, shuffling gait, drooling, mask like face, involuntary movements of the mouth, seizures, brain swelling, dryness of mouth, nasal congestion, headache, nausea, constipation, sexual problems, urinary retention, catatonic like state, cardiac arrest, anemia, skin disorders, increased appetite, weight gain

Medications that may interact: Alcohol, bromocriptine, dofetilide, lithium, pain medications, medications for movement disturbances, medications for digestive system problems, medications for seizures and epilepsy

Prilosec/ Omeprazole

Uses: For heartburn

Potential side effects: Headache, rash, dizziness, constipation, nausea, diarrhea

Medications that may interact: Diazepam, warfarin, phenytoin, ketoconazole, ampicillin esters, iron salts, clarithromycin

Meclizine/ Antivert/ Bonine

Uses: For nausea, vomiting, dizziness associated with motion sickness or vertigo

Potential side effects: Drowsiness, dry mouth, blurred vision

Medications that may interact: Alcohol, barbiturates, injectable antibiotics, digoxin, alprazolam, diazepam, temazepam, allergy medication, depression medication, medications for movement disorders, medications for digestive system problems, pain medications, muscle relaxants

Lactulose/ Cephulac/ Chronulac/ Duphalac

Uses: For chronic constipation

Potential side effects: Gas, cramps, nausea, vomiting

Medications that may interact: Antacids

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Part VIII: Chronic Conditions & Medications


Section C: Chronic Obstructive Pulmonary Disease (COPD)

COPD is the fourth leading cause of death in the United States.1 What is COPD? Chronic obstructive pulmonary disease (COPD) is a term used to describe the obstruction of airflow in the lungs. Primarily, it is associated with two conditions, known as emphysema and chronic bronchitis.

A. Emphysema causes permanent damage to the lungs by weakening and breaking the lungs' air sacs. As a result, the lung tissue looses elasticity, causing the airways to collapse and obstruct airflow.

B. Chronic bronchitis is an inflammatory disease that initially begins in the lungs smaller airways and gradually progresses to the larger airways. Mucus increases in the airways and bacterial infections increase in the bronchial tubes, making it difficult for air to flow in and out of the lungs.2

Long-term smoking is the most frequent cause of COPD. It accounts for 80 to 90 percent of all cases. A smoker is 10 times more likely than a non-smoker to die of COPD. Other risk factors are: hereditary, second-hand smoke, exposure to air pollution at work and in the environment, and a history of childhood respiratory infections.

The symptoms of COPD include: chronic cough, chest tightness, shortness of breath, an increased effort to breathe, increased production of mucus, and frequent clearing of the throat. COPD decreases the lungs' ability to take in oxygen and remove carbon dioxide. As the disease progresses, the lungs small airway walls and alveoli lose their elasticity. The airway walls collapse, closing off some of the smaller air passages and narrowing larger ones. The passageways become blocked with mucus. When the lungs expand during inhalation, air continues to reach the alveoli; however, because the airways tend to collapse while exhaling, it is often unable to escape, trapping the "stale" air in the lungs.³

A typical course of COPD is gradual. It might begin after a person has been smoking for 10+ years, during which symptoms are usually not very noticeable. Then the individual begins developing a productive, chronic cough. Usually, after age 40, the person may complain of shortness of breath during exertion, which continues and worsens over time. Eventually death occurs when the lungs and heart can no longer adequately deliver oxygen to the body's organs and tissues.4 Though the severity of the disease may vary, all persons with COPD have some degree of airway obstruction. Many patients with severe COPD-related lung damage have so much difficulty breathing when lying down that they sleep in a semi-sitting up position.

Cigarette smoking is the most common cause of COPD. But long term exposure to other lung irritants like pollution, dust, paint or other chemicals may cause or contribute to COPD. There is no cure for COPD. Once the damage is done to the lungs and airways, it cannot be reversed. The severity of the symptoms the person has depends largely upon how much lung tissue has been destroyed. The quality of life for the individual diminishes as the disease progresses.

The first and foremost, best treatment to slow or reduce the effects of COPD is to stop smoking. Treatment is always based upon the symptoms, whether they are mild, moderate or severe. Medications and pulmonary (lung) rehabilitation are often recommended to help relieve the symptoms. Flu and pneumonia vaccines are recommended for those with COPD to reduce the chance of getting the flu or pneumonia. For mild cases, short-acting bronchodilators are prescribed. For moderate to severe cases, regular treatments using one or more inhaled short-acting and long-acting bronchodilators and oxygen therapy is generally recommended. In some cases, steroids are prescribed to help reduce inflammation. As a last resort, surgery may be indicated when there is no improvement from medication and the person has difficulty breathing most of the time.

According to the American Lung Association, the annual cost to the country for COPD is about $32.1 billion, $18.0 billion for healthcare expenditures and $14.1 billion for indirect costs.5

References

1National Center for Health Statistics, Report of Final Morbidity Statistics, 1998. Information cited in: American Lung Association, Trends in Chronic Bronchitis and Emphysema: Morbidity and Mortality, December, 2000.

2National Heart, Lung, Blood Institute: Diseases and Conditions Index, US Dept. Health & Human Services, National Institute of Health; Available at: http://dci.nhlbi.nih.gov/Diseases/Copd/Copd_WhatIs.html

3Ibid.

4Ibid.

5American Lung Association. http://www.lungusa.org/diseases/copd_factsheet.html

Resources

American Lung Association - http://www.lungusa.org

American Lung Association
1740 Broadway
New York, NY 10019-4374
1-800-586-4872 (P)

Respiratory Medications

Atrovent Inhaler (ipratropium bromide)

Uses: Used to open airways and decrease the difficulty of breathing associated with chronic obstructive pulmonary disease, chronic bronchitis, and emphysema

Potential side effects: Tachycardia, paresthesias, drowsiness, coordination difficulty, itching, hives, flushing, alopecia, constipation, tremor, and mucosal ulcers, dry throat, cough

Medications that may interact: Atropine, hyoscyamine

Diphenhydramine (Banophen, Benadryl)

Uses: For relief from symptoms of upper respiratory allergies, runny nose, sneezing, itchy, watery eyes, itching of the nose or throat

Potential side effects: Drowsiness, dry mouth, dry eyes

Medications that may interact: Alcohol, sedatives, and tranquilizers, Monoamine oxidase (MAO) inhibitors, other allergy medications, sleeping and anxiety medications,

Do not use with any other product containing diphenhydramine, including one applied topically.

Serevent (Salmeterol inhalation aerosol)

Uses: Asthma, emphysema, chronic bronchitis

Potential side effects: Tachycardia, palpitations, urticaria, angioedema, rash, bronchospasm, headache, tremor, nervousness, and paradoxical bronchospasm

Medications that may interact: Monoamine oxidase inhibitors, tricyclic antidepressants, and beta blockers

Vanceril (Beclomethasone inhalation aerosol, Beclovent, Qvar, Vancenase AQ)

Uses: For the treatment of asthma

Potential side effects: Irritation and burning in the nose, sneezing

Medications that may interact: Prednisone

Albuterol, Proventil, Ventolin

Uses: For asthma and chronic bronchitis

Potential side effects: Tachycardia, palpitations, urticaria, angioedema, rash, bronchospasm, headache, tremor, nervousness, and paradoxical bronchospasm

Medications that may interact: Other short-acting sympathomimetic aerosol bronchodilators, beta-blockers, nonpotassium-sparing diuretics, digoxin, and monoamine oxidase inhibitors

Theophylline (Theo 24, Theolair, Bronkodyl, Uniphyl, Aminophylline)

Uses: Chronic asthma, emphysema, chronic bronchitis

Potential side effects: Nausea, vomiting, headache, insomnia, diarrhea, irritability, restlessness, tremors, and transient diuresis

Medications that may interact: Cimetidine, erythromycin, tacrine, carbamazepine, rifampin, diazepam, enoxacin, ephedrine, halothane, interferon, lithium, mexiletine, thiabendazole

Hismanal (Astemizole tablets)

Uses: For hives and hayfever

Potential side effects: Agitation, nervousness, excitability, insomnia, heart palpitations

Medications that may interact: Bosentan, erythromycin, clarithromycin, cisapride, ziprasidone, pimozide, nefazodone, fluoxetine, paroxetine, sertraline, fluconazole, itraconazole, ketoconazole, voriconazole, grapefruit juice

Claritin (Loratadine tablets, Alavert)

Uses: For hayfever and hives

Potential side effects: Dry mouth, headache, drowsiness

Medications that may interact: Clarithromycin, erythromycin, fluconazole, itraconazole, ketoconazole, voriconazole

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Part VIII: Chronic Conditions & Medications


Section D: Falls and Accidents

Accidental injuries are the eighth leading cause of deaths among adults age 65 or older, and they are the major cause of disabilities and hospitalizations. Fall and fall-related injuries are the leading cause of accident in people over age 65 and the leading cause of injury death among those 85 or older. Hip fractures are one of the most serious outcomes associated with falls. Half of all older adults hospitalized for hip fractures cannot return home or live independently after their injuries.1 Most falls and injuries occur where older adults spend the majority of their time in the home. Research has determined that most fall-related injuries occur on the same level (not while walking on stairs) and from a standing position (such as tripping while walking). AARP's Public Policy Institute reported 14% of falls took place on stairs or steps, 9% while rising or sitting on a bed, chair or other furniture and 4% took place in the bathroom.2

Several factors can cause an older adult to fall such as age-related changes including poor eyesight or poor hearing. Chronic conditions and illnesses can affect coordination, balance and strength. Extrinsic environmental conditions such as, poor lighting, clutter, certain shoe styles, or throw rugs can increase the risk of falling. Certain medications can affect balance, vision, cognition and reaction time. According to the American Academy of Family Physicians, falls are likely to occur in persons taking four or more medications or if they have had a change in their medication within the past two weeks. Falls can also be an indicator of poor health and functional decline.3 Researchers have determined that those elderly persons who do fall experience more difficulty in performing activities of daily living, participating in physical and social activities and have a greater risk of institutionalization. A recent study compared two groups of individ uals that fall with those that had not fallen while receiving in-home health care services. Those that reported falling had a history of falling three times more often, had a history of cardiovascular and neurological impairments, and took more medications that were known to contribute to a higher risk for falls compared to those that had not fallen.4

Another disability caused by falls is the fear of falling again. People who have fallen often cope by restricting their activity. Between 10 and 25 percent of people who have fallen admit to avoiding activities such as shopping or housekeeping because of their fear of falls.

Family members and other caregivers may also discourage certain activities. It is important that the person receives emotional support. Decreased activities lead to de-conditioning in which muscles become weaker. Severe immobility can lead to complications such as contractures of the joint. This cycle increases the older person's risk of falls and contributes to functional decline.

Task-oriented service delivery systems tend to promote learned helplessness in elders, therefore promoting this vicious cycle. Many elders are afraid to tell anyone they have fallen for fear of a change in lifestyle, such as, losing independence. A rehabilitation model that promotes assistive technology strategies can assist the older person toward completing a task safely, independently and in a timely manner. Using assistive technology and home modification strategies are important in terms of quality of life and cost effectiveness.

Fear of Falling Cycle
Fear of falling diagram

Note: Start with letter A. and go clockwise ending back at letter A.

For the elderly, fractures are the most serious problem associated with falls. Hip fractures are the most serious and create the greatest number of health problems and death. The number of hip fractures increase with age. Women have a greater risk of hip fractures due to thinning of the bones, hormonal changes, osteoporosis, etc. Direct treatment of a hip fracture is very costly. In the U.S., it may cost in excess of $70 million dollars. This figure does not take into consideration the additional cost for long-term or post-hospitalization care.

Falls: Risk/Causative Factors

Intrinsic Factors

Extrinsic

Factor type

Factors

Factor type

Factors

Physiological

neurological
musculoskeletal
sensory - vision

Environmental

obstacles
lighting
surfaces
assistive devices
clothing
footwear

Pathological

alcohol
medication
disorders

Falls for the most part are preventable and should not be regarded as an expected outcome of aging. Even older people who appear to be healthy and strong can fall. Falls are a threat to older people's ability to live on their own. Below are some strategies that are recommended for anyone working with the elderly to help prevent falls.

• Provide education and information on gait training and appropriate use of assistive devices used for balance.

• Encourage them to participate in a regular exercise program that promotes balance and strength training.

• Medications should be reviewed regularly to check for side effects and possible drug reactions. Older people taking more than four medications are susceptible to falls.

• Screening for conditions that can affect balance and coordination, such as, osteoporosis, postural hypotension, other cardiovascular disorders and other irregular rhythm to the heart. Those detected should be treated.

• Consider bone-strengthening medications such as hormone replacement therapy (HRT), calcium or vitamin D to reduce risk of fall-related fractures.

• Evaluate the home environment for hazards such as scatter rugs, clutter, or poor lighting. (See environment section for more details).

• Recommend shoes that are supportive with non-slip soles.

• Recommend using anatomically designed external hip protectors to help decrease the risk of hip fractures.5

• Involve the family.

References

1Center for Disease Control, Department of Health and Human Services, "Health Aging: Preventing Disease and Improving Quality of Life Among Older Americans (2003)." Available at http://www.cdc.gov/nccdphp/aag/aag_aging.htm.

2"Don't Let Falls Get You Down," Dynamic Living Newsletter, Feb 2004, Vol.60. Available at www.dynamic-living.com.

3Fuller, George F., "Falls in the Elderly," American Family Physician, 2000. Available at: http://www.aafp.org/afp/20000401/2159.html.

4Lewis CL, Moutoux M, Slaughter M, Bailey SP. "Characteristics of individuals who fell while receiving home health services," Physical Therapy, 2004; 84(1): 23-32.

5Kannus, P., Parkkari, J., Miemi, S., Pasanen, M., Palvanen, M., Javinen, M., Vuori, I. Prevention of hip fracture in elderly people with use of a hip protector. New England Journal of Medicine (2000): 343: 1506-13.

Resources

Safety Checklists:

Check for Safety, A Home Fall Prevention Checklist for Older Adults. Centers for Disease Control, U.S. Department of Health and Human Services
Available at: http://www.cdc.gov/ncipc/pub-res/toolkit/checkforsafety.htm

Safety for Older Consumers Home Safety Checklist. Consumer Product Safety Commission. Available at: http://www.cpsc.gov/cpscpub/pubs/701.html

Home Safety Checklist. Rebuilding Together. Available at: http://www.rebuildingtogether.org/home_modifications/Checklist.pdf

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Part VIII: Chronic Conditions & Medications


Section E: Diabetes

Diabetes is a metabolism disorder. This disease affects more women than men. It is more prevalent among African Americans and Hispanics than among Caucasians. Most of the food we eat is broken down into a form of sugar called glucose. The body uses it for growth and energy. Glucose is found in the blood and serves as the body's main source of fuel.

After digestion, glucose passes into the bloodstream, where it is used by the cells for growth and energy. The pancreas produces a hormone called insulin that must be available to help glucose cross over into the cells.

The pancreas automatically produces the correct amount of insulin to move glucose from the blood into the cells. But for people with diabetes, the pancreas either produces little or no insulin or the cells don't respond correctly to the insulin that is produced. This causes glucose to build up in the blood, overflow into the urine, and pass out of the body. When this happens, the body loses its main fuel source. If this isn't controlled, the glucose and fats remain in the blood, which overtime damages vital organs.

According to the Centers for Disease Control, diabetes is the sixth leading cause of death among Americans. It is most common in older people, women, overweight and sedentary people, African Americans, Alaska Natives, American Indians, Asian and Pacific Islander Americans, and Hispanic Americans.

Diabetes can affect almost every part of the body. This disease often leads to blindness (diabetic neuropathy), heart and blood vessel disease, strokes, kidney failure, amputations, and nerve damage (peripheral neuropathy). Women with uncontrolled diabetes can experience complicated pregnancies and birth defects.

There are two types of diabetes: Type 1 and Type 2

Type 1 diabetes

Type 1 diabetes is an autoimmune disease that occurs when the body's own immune system turns against a part of the body when it is fighting infection. The immune system attacks the insulin producing cells in the pancreas and destroys them. This causes the pancreas to produce little or no insulin. Persons with Type 1 diabetes need to take insulin (oral, injection, or pump) daily to live.

Some of the symptoms the person with diabetes will experience are increased thirst and urination, constant hunger, weight loss, blurred vision, and extreme fatigue. If not diagnosed and treated with insulin, a person can fall into a life-threatening diabetic coma.

Healthy eating, physical activity, and insulin via injection or an insulin pump are the basic therapies for Type 1 diabetes. The amount of insulin must be balanced with food intake and daily activities. Blood glucose levels must be closely monitored through frequent blood glucose checking.1

Type 2 diabetes

Type 2 diabetes is the most common form of diabetes. About 90 to 95 percent of people with diabetes have Type 2. It usually develops in adults, age 40 and older and is most common in adults over age 55. Reports indicate about 80% of people with Type 2 diabetes are overweight. Those with Type 2 diabetes often are diagnosed with a metabolic syndrome that includes obesity, elevated blood pressure, and high levels of blood fats.

With Type 2 diabetes, the pancreas is able to produce enough insulin, but cannot use the insulin effectively. This is called insulin resistance. After a number of years, insulin production decreases. The result is the same as for Type I diabetes, glucose builds up in the blood and the body cannot make efficient use of it.

The symptoms of Type 2 diabetes develop overtime. They are not as sudden in onset as in Type 1 diabetes. Some people have no symptoms. When symptoms are present they may include: fatigue or nausea, frequent urination, unusual thirst, weight loss, blurred vision, frequent infections, and slow healing of wounds or sores. Some of the complications of diabetes for the mature adult are: heart disease, stroke, high blood pressure, blindness, kidney disease, nervous system disease, high cholesterol, amputations, and dental disease.

As with Type 1 diabetes, healthy eating, physical activity, and blood glucose testing are the basic management tools for Type 2 diabetes. In addition, many people with Type 2 diabetes need oral medication and insulin to control their blood glucose levels.

Treatment

It is very important that people with diabetes take responsibility for their day-to-day care. This involves keeping blood glucose levels from getting too high or too low. When the glucose level drops too low it is known as hypoglycemia. The person will become nervous, shaky, and confused. Judgment can be impaired. If blood glucose falls too low, a person can faint. A condition known as hyperglycemia occurs if the blood glucose levels rise too high. The person can become quite ill.

"The risk for death among people with diabetes is about two times that of people without diabetes."2 People with diabetes should see a doctor who can help them learn to manage and monitor their diabetes. An endocrinologist is one type of doctor who may specialize in diabetes care. In addition, people with diabetes often see ophthalmologists for eye examinations, podiatrists for routine foot care, and dietitians and diabetes educators to help learn the skills of day-to-day diabetes management.3 According to the American Diabetes Association, in 2002, there were an estimated 12.1 million people in America diagnosed with diabetes. For the U. S., this disease cost about $132 billion in medical expenditures and lost productivity. Due to the high incidence of diabetes, it is estimated that over $92 billion was spent for direct medical care costs.

References

1http://diabetes.niddk.nih.gov/

2http://diabetes.org/main/info/facts/facts_natl.jsp

3http://diabetes.niddk.nih.gov/

Resources

American Diabetes Association - http://diabetes.org
National Call Center
1701 North Beauregard Street
Alexandria, VA 22311
1-800-342-2383
Center for Disease Control Diabetes Public Health Resource: www.cdc.gov/diabetes
Diabetes Resource Center: www.diabetesresourcecenter.org
Juvenile Diabetes Research Foundation: www.jdf.org
National Diabetes Education Program: www.ndep.nih.gov
National Institute of Diabetes & Digestive & Kidney Diseases: www.niddk.nih.gov/

Diabetes Medications

Humulin injection (Insulin, Iletin II, Humalog, Novolin, Novolog)

Uses: For diabetes to control blood sugar

Potential side effects: Hypoglycemia associated symptoms: sweating, dizziness, palpitation, tremor, hunger, restlessness, tingling, lightheadedness, decreased concentration, headache, drowsiness, sleep disturbances, anxiety, blurred vision, slurred speech, depression, irritability, abnormal behavior, unsteady movement, personality changes, disorientation, unconsciousness, seizures, death; diabetic acidosis symptoms: fatigue, flushing, thirst, decreased appetite, and fruity smelling breath

Medications that may interact: Corticosteroids, thyroid replacement therapy, oral hypoglycemics, salicylates (aspirin), sulfa antibiotics, and some antidepressants

Glyburide tablets/ Diabeta (Glynase, Micronase)

Uses: For management of diabetes

Potential side effects: Visual disturbances, hypoglycemia and diabetic acidosis (as with Humulin)

Medications that may interact: Nonsteroidal anti-inflammatory agents, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, beta blockers, fluoroquinolone antibiotics, coumarin derivatives, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, isoniazid

Chlorpromapide (Diabinese)

Uses: For management of diabetes

Potential side effects: Gastrointestinal disturbances, nausea, hypoglycemia and diabetic acidosis (as with Humulin)

Medications that may interact: Barbiturates, alcohol, nonsteroidal anti-inflammatory agents, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta blockers, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, isoniazid

Glucophage (Metformin)

Uses: For management of diabetes

Potential side effects: Diarrhea, nausea, vomiting, flatulence, asthenia, indigestion, abdominal discomfort, headache

Medications that may interact: Alcohol, nifedipine, amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, isoniazid

Glucotrol (Glipizide)

Uses: For management of diabetes

Potential side effects: Nausea, diarrhea, skin rash, sun sensitivity, dizziness, drowsiness, headache, hypoglycemia (as with Humulin)

Medications that may interact: Nonsteroidal anti-inflammatory agents, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta blockers, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, isoniazid, oral miconazole and oral hypoglycemic agents, fluconazole

Rezulin (Troglitazone)

Uses: For management of diabetes

Potential side effects: Swelling, headache, nausea, vomiting

Medications that may interact: Astemizole, fexofenadine, terfenadine, carbamazepine, cisapride, cyclosporine, alprazolam, diazepam, midazolam, triazolam, diltiazem, felodipine, lidocaine, nifedipine, quinidine, verapamil, cholestyramine, lovastatin, simvastatin, donepezil, erythromycin, indinavir, other medicines for diabetes, saquinavir, voriconazole

Tolinase (tolazamide tablets)

Uses: For management of diabetes

Potential side effects: Dizziness, fatigue, headache, heartburn, stomach discomfort, sun sensitivity, nausea, vomiting, skin rash, hypoglycemia (as with Humulin)

Medications that may interact: Alcohol, beta-blockers, cisapride, clofibrate, diazoxide, itraconazole, miconazole, voriconazole, metoclopramide, rifampin, warfarin

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Part VIII: Chronic Conditions & Medications


Section F: Pneumonia/Flu

Pneumonia

According to the American Lung Association, pneumonia is a serious infection or inflammation of the lungs. Pus and other liquid fill the lung's air sacs making it difficult for oxygen to reach the blood. Without enough oxygen in the blood, the body cells cannot work well. Because of this and the spreading of infection through the body, pneumonia can cause death. The lungs can be affected two ways: 1) lobar pneumonia affects a section (lobe) of a lung and 2) bronchial pneumonia affects patches throughout both lungs.1

Pneumonia is not a single disease. It can have over 30 different causes. The five main causes of pneumonia are: bacteria, viruses, mycoplasmas, fungi, and various chemicals.

There are two types of pneumonia: bacterial and viral:

Bacterial Pneumonia

Any age group (young and old) can be diagnosed with bacterial pneumonia. But some have a greater risk than others, such as alcoholics, the debilitated, post-operative patients, people with respiratory diseases or viral infections and people who have weakened immune systems.

Pneumonia bacteria can be found in some healthy throats. When body defenses are weakened in some way, either by illness, old age, malnutrition, general weakness or impaired immunity, the bacteria can multiply and cause serious damage. Usually, when a person's resistance is lowered, bacteria work their way into the lungs and inflame the air sacs. The onset can vary from gradual to sudden.

The lungs have five lobes. Bacterial infection can attack any part of the lungs' tissue, part or all the lobes which will cause the lobes to fill with fluid. Very little time is needed for the infection to spread through the bloodstream to other parts of the body.

Streptococcus pneumoniae is the most common cause of bacterial pneumonia. It is one form of pneumonia for which a vaccine is available. Once a vaccine is taken, it is good for life.

Symptoms

The Lung Association states, that "in severe cases, the patient may experience shaking chills, chattering teeth, severe chest pain, and a cough that produces rust-colored or greenish mucus, increased breathing and pulse rate, body temperature may rise as high as 105ºF and bluish colored lips or nails due to lack of oxygen."2

Viral Pneumonia

Almost half of all pneumonias are believed to be caused by viruses, yet most of these pneumonias are not serious and last a short time. Through research, numerous types of viruses are being identified as the cause of respiratory infection. Though most affect the upper respiratory tract, some do produce pneumonia.

The most severe and occasionally fatal virus that aggressively invades the lungs and multiplies is the influenza virus. There are almost no physical signs that fluid fills the lung tissue. Those with pre-existing heart or lung disease or are pregnant are most effected.3

Symptoms

Initially the symptoms of viral pneumonia are similar to influenza symptoms: presence of fever, a dry cough, headache, muscle pain, and weakness. But within 12 to 36 hours, the person will have increasing difficulty in breathing and develop a high fever. The cough becomes intense and produces a small amount of mucus. The lips will appear blue.

According to the Lung Association, those with extreme symptoms will have a desperate need for air and extreme breathlessness. Viral pneumonias may be complicated by an invasion of bacteria, with all the typical symptoms of bacterial pneumonia.4

Pneumonia prevention

How can pneumonia be prevented? Because pneumonia is a common complication of influenza (flu), getting a flu shot every fall is good pneumonia prevention.

A vaccine is also available to help fight pneumococcal pneumonia, one type of bacterial pneumonia. Usually, it is given only once to those individual at high risk of getting the disease and its life-threatening complications.

Those people who are at the greatest risk of pneumococcal pneumonia:

• Have chronic illnesses such as lung disease, heart disease, kidney disorders, sickle cell anemia, or diabetes.

• Are recovering from severe illness.

• Are in nursing homes or other chronic care facilities.

• Are age 65 or older.

• Have history of respiratory problems such as reactive airway disease or asthma.

Good health habits, proper diet and hygiene, rest, regular exercise, etc. increase resistance to all respiratory illnesses and help promote fast recovery when illness does occur.

Influenza (Flu)

Flu is a contagious disease caused by a virus that affects the respiratory system primarily the ears, nose and throat. Since it is caused by a virus, an antibiotic is not recommended for treatment. It is different from the common cold. It attacks the body very quickly and the person may start to experience some or all of the symptoms listed below:

• Fever

• Headache

• Tiredness (can be extreme)

• Dry cough

• Sore throat

• Nasal congestion

• Body aches

Recovery time varies among people but usually lasts between one to two weeks. Some people may be prone to develop pneumonia, a life-threatening condition, as a result of the flu. According to the CDC, about 10% to 20% of the population will get the flu each year. The flu can attack anyone at any age. Those people over age 65 with chronic conditions and those who are very young can develop complications from the flu. Three types of complications that occur are bronchitis, pneumonia, sinus and ear infections. Chronic conditions such as asthma and congestive heart failure can become much more serious.5

The flu virus spreads from person to person. The infected person can transfer the virus through the air by sneezing, coughing, or speaking to another person. The other person contracts the illness by inhaling the virus through the nose. For some people, symptoms can occur within one to three days after exposure to the virus while others may not show any symptoms but still be carriers of the virus. The virus can spread to others for 3-7 days after an adult shows symptoms and longer than 7 days for children. Since the flu is caused by a virus, antibiotics will have no effect on it. The best treatment for the flu is to:

• Rest

• Drink plenty of liquids

• Avoid using alcohol and tobacco

• Take medication to relieve the symptoms of flu6

According to the American Lung Association, pneumonia and influenza combined ranked as the seventh leading cause of death for the year 2000.

When should you get your flu vaccine?

Group of People

When to Get YOUR Vaccine

High Risk of Severe Illness

• 65 years old or older
• Children 6 - 23 months old
• Adults and children with chronic health conditions
• More than 3 months pregnant during the flu season
   

Close Contacts of People at High Risk of Severe Illness

• Household member or caregiver for someone at high risk
• Healthcare workers
• Household member or caregiver for children under 2 years old

Child Getting a First Flu Shot Ever

October or November is the best time to vaccinate!

December is not too late!

Healthy People 50-64 Years Old

Anyone Who Wants to Prevent the Flu


Table available at: http://www.cdc.gov/nip/Flu/Public.htm#true7

 

References

1http://www.dupagehealth.org/health_data/adobe_pdf/leading-causes-of-death.pdf

2http://www.lungusa.org/diseases/lungpneumoni.html

3http://www.lungusa.org/diseases/lungpneumoni.html

4http://www.lungusa.org/diseases/lungpneumoni.html

5http://www.cdc.gov/flu/about/disease.htm

6http://www.cdc.gov/ncidod/diseases/flu/fluinfo.htm

7When should you get a flu vaccine? Table available from: http://www.cdc.gov/nip/Flu/Public.htm#true

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Part VIII: Chronic Conditions & Medications


Section G. Alzheimer's Disease and Dementia

About 4.5 million Americans over 65 have Alzheimer's disease.1 Occurrence of this disease doubles every five years beyond age 65. Alzheimer's disease continues to be a mystery. But it is known to cause a gradual loss of brain cells.

Dementia is a "catch term" used to describe symptoms related to the decline of thinking skills. These symptoms include the following:

• Gradual loss of memory (frequent and inexplicable states of confusion)

• Difficulty with reasoning or poor judgment (allow strangers in the home)

• Disorientation (might be on their own street and no longer know where they are, how they got there and how to get home again)

• Difficulty in learning new tasks

• Decreased language skills (cannot remember simple words, uses fillers making it difficult for the listener to understand)

• Decrease in ADL function (does not always choose clothes suitable for the weather, may wear underwear as outerwear)

• Personality and behavior changes (anxiety, agitation, sudden mood swings, delusions, hallucinations, wandering, sleeplessness)

According to Dementia.com, "the frequency of dementia increases with advancing age (less than 2% for 65-69-year-olds, to 5% for 75-79 year-olds and to more than 20% for 85-89 year-olds). Every third person over the age of 90 suffers from moderate or severe dementia. About half of those affected by dementia suffer from Alzheimer's disease. About 5% of people above 65 years of age, about 20% of those over 80 years and about 30% of those over 90 suffer from Alzheimer's disease."2

Alzheimer's disease is typically divided into three stages:

1. Mild or Early Stage (impairment of mental abilities and mood swings)

2. Moderate or Mid-Stage (increase in behavioral disturbances)

3. Severe or Late-Stage (physical problems are dominant)

There is no cure for cognitive impairment or Alzheimer's disease. But there are treatments for each stage:

1. Mild stage: Cognitive training of thinking and memory, but use caution as not to constantly remind the person of his/her declining abilities.

2. Moderate stage and severe stage: Caregiver takes steps to address the organization and care of the person's environment, such as placing notes or signs as reminders. For someone that may run into glass patio doors, a colored decal or a stop sign placed on the door will cue the person to stop proceeding.

Caregiving tasks can be difficult. Andrea Tannebaum, President of Dynamic-Living states, "It is one of the toughest jobs anyone can ever have. Not only must caregivers deal with an exhausting physical routine but a difficult emotional burden, too. They often feel alone, not sure where to turn for support or for practical knowledge they need."3 For those in the moderate to severe stage, family members are forced to become more and more responsible for the health, welfare, and basic activities of daily living.

According to the Alzheimer's Association, both the caregiver and the individual with Alzheimer's disease may experience the following reactions: depression, denial, anxiety and fear, isolation and loneliness, embarrassment and shame, and feelings of loss. It is important to address any of these reactions. Referrals to an Alzheimer's Association support group, short-term counseling and medications and a physician knowledgeable in dementia for assessment and treatment can help the family deal with their reactions to the disease.

Family dynamics change when a loved one is diagnosed with Alzheimer's disease and can cause stress within family relationships.

Individuals with early-stage Alzheimer's may experience:

• feelings of people trying to help too much or too little,

• primary role changes in their relationship,

• anxiety over whom they should tell about the diagnosis,

• feelings of misunderstanding by others,

• difficulty trusting their own decision making,

• withdrawal or avoidance of family and friends,

• difficulty with social interaction,

• increase or decrease in sexual desire, and

• increased anxiety over financial and legal issues.

Caregivers may experience:

• role changes within the relationship,

• anxiety over who should know about the diagnosis,

• changes in the sexual relationship,

• and feeling misunderstood by family and friends, which could lead to isolation.

It is very important to address all the feelings experienced by those involved to include the individual with Alzheimer's in the decision-making process, and to encourage family and friends to be open about the changes that are taking place. Talking about problems, concerns, and solutions can help resolve stress and tension early on.4

References

1Alzheimer's Association: http://www.alz.org/AboutAD/WhatIsAD.asp

2http:// www.dementia.com

3http://dynamic-living.com

4Alzheimer's Association. "Understanding Early-Stage Alzheimer's Disease," (1999): Available at http://www.alz.org

Resources

American Alzheimer's Association - http://www.alz.org

The Alzheimer's Association is the world leader in Alzheimer research and support. Since their establishment in 1980, they have provided more than $150 million to support research into the prevention, treatment and eventual cure for Alzheimer's. Their mission is to eliminate Alzheimer's disease through the advancement of research and to enhance quality care and support for individuals, their families and care partners.

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Part VIII: Chronic Conditions & Medications


Section H. Kidney Disease

The function of a healthy kidney is to remove extra water and wastes, help regulate blood pressure, maintain balance among body chemicals, keep strong bones and produces red blood cells. When the kidneys are unable to clean the blood of waste products and toxins, chronic kidney disease occurs. This can occur very quickly (acute) or over a long period. Most kidney disease is caused by diabetes and high blood pressure, conditions that can run in families.

"Acute renal failure means the kidneys have failed suddenly, often due to a toxin (a drug allergy or poison) or severe blood loss or trauma. Dialysis is used to clean the blood and give the kidneys a rest. If the cause is treated, the kidneys may be able to recover some or all of their function."1

It is important to recognize the symptoms of kidney disease so that it can be diagnosed and treated early. Some of the symptoms of acute renal failure are as follows:

• Changes in urination - frequent urination or decreased urgency, feeling pressure when urinating, changes in urine color, foamy or bubbly urine, or interrupted sleep due to getting up at night to urinate.

• Swelling of the feet, ankles, hands, or face - kidneys can't remove excess fluid and it may stay in the tissues.

• Fatigue or weakness - caused by a build-up of wastes or a shortage of red blood cells (anemia) when the kidneys begin to fail.

• Shortness of breath - fluid can begin to build up in the lungs. Sometimes it can be confused with asthma or heart failure.

• Ammonia breath or an ammonia or metal taste in the mouth - caused by waste build-up in the body. The person may have an aversion to protein foods, meat and eggs.

• Back or flank pain - at the site where the kidneys are located on either side of the spine in the back.

• Itching - occurs in the legs especially when waste builds-up in the body.

• Loss of appetite

• Nausea and vomiting

• More hypoglycemic episodes, if diabetic. (For other details, see Diabetes section).

High blood pressure is one of the leading causes of kidney failure which is also commonly called end-stage renal disease (ESRD). People with kidney failure must either receive a kidney transplant or go on dialysis. Every year, high blood pressure causes more than 15,000 new cases of kidney failure in the United States.

The National Heart, Lung and Blood Institute found that five lifestyle changes can help control blood pressure:2,3

• Maintain your weight at a level close to normal. Choose fruits, vegetables, grains, and low-fat dairy foods.

• Limit your daily sodium (salt) intake to 2,000 milligrams or lower if you already have high blood pressure. Read nutrition labels on packaged foods to learn how much sodium is in one serving. Keep a sodium diary.

• Get plenty of exercise, at least 30 minutes of moderate activity on most days of the week, such as walking.

• Avoid drinking too much alcohol. Men should limit drinking to two drinks (two 12-ounce servings of beer or two 5-ounce servings of wine or two 1.5-ounce servings of "hard" liquor) a day. Women should have no more than one serving daily. Due to metabolic differences, women are more susceptible.

• Limit caffeine intake.

For more details, see the High Blood Pressure section.

References

1http://www.davita.com/education/kidney_disease/about_chronic_kidney_disease/01.cfm?CMP=KNC-ZO3292772175

2National Kidney and Urological Disease Information Clearinghouse http://kidney.niddk.nih.gov/kudiseases/pubs/highblood/index.htm#2

3National Heart, Lung, and Blood Institute: http://www.nhlbi.nih.gov/hbp/prevent/prevent.htm

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Part VIII: Chronic Conditions & Medications


Section I. Arthritis

The CDC estimates that arthritis will affect 60 million Americans by 2020. Presently, one in three people age 50 and over have arthritis. It is known as the leading cause of disability among the U. S. population.1 The Administration on Aging (AoA) reports that there are cost-effective interventions available to reduce the effects of arthritis, but often are not used.2 Typical symptoms of arthritis are pain, swelling, and stiffness near the joints. The word arthritis literally means "joint inflammation."3 It has been estimated that there are over 100 types of arthritis.

The National Academy on an Aging Society compared individuals with arthritis with those that do not have the condition and found that individuals with arthritis are likely to experience more physical and occupational limitations, have more financial difficulties, are less satisfied with their current circumstances and are less optimistic about the future. They found that the elderly age 70+ with arthritis are more likely to have stayed in a nursing home. Ninety-four percent of these elders use prescription medication and use a variety of services, such as Meals on Wheels, social worker, adult day care, rehabilitation and transportation.

Osteoarthritis (OA)

Osteoarthritis is one of the most common chronic conditions affecting middle-aged and older adults. The Arthritis Foundation defines "osteoarthritis or degenerative joint disease as one of the oldest and most common types of arthritis. It is characterized by the breakdown of the joint's cartilage. Cartilage is the part of the joint that cushions the ends of bones. Cartilage breakdown causes bones to rub against each other, causing pain and loss of movement." Its symptoms can range from very mild to very severe. It affects hands and weight-bearing joints such as knees, hips, feet and the back. It affects an estimated 20.7 million Americans, mostly after age 45. It commonly affects women more than men. "It is the leading cause of disability in older people and costs the American economy about $124.8 billion annually. This figure includes medical expenses and lost productivity. The older population is growing rapidly, the Centers for Disease Control and Prevention projects that osteoarthritis will affect almost 60 million people by 2020."4

Although it affects those who are middle-aged or elderly, it is not caused by the effects of aging. Obesity may lead to osteoarthritis in the knees due to excessive weight bearing on the joints. Also, any person with joint injuries resulting from sports, work-related activity or accidents may increase their risk of developing OA. Scientists believe that genetics may also cause osteoarthritis in the hands over time.

Osteoporosis

Osteoporosis affects both men and women and puts them at greater risk for fractures. Women are at the greatest risk because they start with less bone mass than men. Osteoporosis causes the bones to lose strength and break easily as the person ages. After menopause, women lose bone mass much more quickly. According to the Arthritis Foundation, as the person ages, their body loses more older bone than the body can replace with new bone tissue. AoA reports that one out of two post-menopausal women will have an osteoporosis-related fracture in her lifetime.

There is no cure for osteoporosis. It is largely preventable and is not a natural part of aging. It is closely associated to fractures and falls and can be prevented by good nutrition and exercise. The National Osteoporosis Foundation reports that the best defense from developing osteoporosis is to develop strong bones and develop a healthy lifestyle before the age of 30.

References

1http://www.cdc.gov/nccdphp/arthritis/index.htm

2http://www.aoa.gov/eldfam/healthy_lifestyles/art_ost/art_ost_pf.asp

3Williams & Wilkins, Stedman's Medical Dictionary, 24ed., p.124.

4Alliance for Aging Research, Webzine, Issue 18, Fall 2003, www.agingresearch.org/living/signin newsletter.cfm.

Resources

Arthritis Foundation - http://www.arthritis.org
National Office
1330 West Peachtree Street
Atlanta, GA 30309
1-800-283-7800 (P)

Arthritis Medications

Tylenol (Acetaminophen) with Codeine

Uses: Used for mild to moderate pain

Potential side effects: Mental alteration, lightheadedness, dizziness, sedation, vomiting, nausea, and shortness of breath, allergic reactions, euphoria, dysphoria, constipation, abdominal pain and pruritus

Medications that may interact: Anticholinergics, other narcotic analgesics, antipsychotics, antianxiety agents, other CNS depressants, and alcohol

Ibuprofen (anti-inflammatory drug)

Uses: Used to relieve minor aches and pains, temporarily reduces fever

Potential side effects: Upset stomach (may be relieved if taken with food or milk), stomach bleeding

Medications that may interact: Alcohol, other anti-inflammatory drugs, methotrexate, warfarin, high blood pressure medications, diuretics, and lithium

DayPro (Oxaprozin)

Uses: For fever, inflammation, and mild to moderate pain

Potential side effects: Ulcer, visual disturbance, increased urination, stomach pain, swelling, constipation, diarrhea, difficulty sleeping, drowsiness, gas, heartburn, nausea, vomiting

Medications that may interact: Alcohol, alendronate, aspirin, cidofovir, cyclosporine, drospirenone, ethinyl estradiol, lithium, blood pressure medications, platelet medications, blood thinners, methotrexate, ibuprofen, prednisone, diuretics

Methotrexate sodium tablets

Uses: Used for gestational choriocarcinoma, chorioadenoma destruens, hydatidiform mole, acute lymphocytic leukemia, meningeal leukemia, non-metastatic osteosarcoma, breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides, lung cancer, advanced stage non-Hodgkin's lymphomas, severe psoriasis, and severe rheumatoid arthritis

Potential side effects: Ulcerative stomatitis, leukopenia, nausea, abdominal distress, depression, fatigue, chills, fever, dizziness, and decreased ability to fight infection

Medications that may interact: Alcohol, non-steroidal anti-inflammatory drugs, salicylates, phenylbutazone, phenytoin, and sulfonamides, cisplatin, oral antibiotics, penicillins, azathioprine, retinoids, sulfasalazine, and theophylline

Naproxin

Uses: For relief of mild to moderate pain

Potential side effects: Constipation, heartburn, abdominal pain, and nausea, peptic ulcers, headache, drowsiness, dizziness, vertigo, lightheadedness, decreased concentration, depression, agitation, irritability, fatigue, sleep disorders, swelling, rash

Medications that may interact: Oral anticoagulants, hydantoins, salicylates (aspirin), sulfonamides, sulfonylureas, anticoagulant or thrombolytic agent, probenecid, methotrexate, lithium, prednisolone, furosemide, angiotensin-converting enzyme (ACE) inhibitors, antacids

Prednisone (Deltasone)

Uses: For relief of swelling, redness, itching, and allergic reactions and can be used to treat severe allergies, skin problems, asthma, and arthritis

Potential side effects: Confusion, excitement, restlessness, visual disturbances, decreased ability to fight infection, depression, muscle cramps, weakness, nausea, vomiting, round face, increased thirst, irregular heart rhythm, swelling, weight change, skin problems, diarrhea, headache, constipation, change in appetite, upset stomach, hair growth on face or body

Medications that may interact: Acetazolamide, anti-inflammatory drugs, barbiturates, bosentan, heart medications, diabetes medications, phenytoin, rifabutin, rifampin, diuretics, warfarin

Darvocet (Acetaminophen/ Propoxyphene, Propacet, Wygesic, E-Lor, Propoxacet N)

Uses: For relief of mild to moderate pain

Potential side effects: Mental alteration, dizziness, sedation, nausea, vomiting, constipation, abdominal pain, skin rashes, lightheadedness, headache, weakness, euphoria, dysphoria, hallucinations and minor visual disturbances

Medications that may interact: Sedatives, tranquilizers, muscle relaxants, antidepressants, other CNS-depressant drugs, alcohol, salicylates, and carbamazepine.

Indomethacin(Indocin, anti-inflammatory drug)

Uses: For pain associated with severe arthritis, ankylosing spondylitis, and gout

Potential side effects: Headache, dizziness, nausea, vomiting, indigestion, heartburn

Medications that may interact: Aspirin or other salicylates, diflunisal, other non-steroidal anti-inflammatory drugs, probenecid, methotrexate, cyclosporine, lithium, digoxin, diuretics, furosemide, triamterene, captopril, and losartan

Arthritis Resources

Arthritis Foundation: www.arthritis.org
Arthritis Resource Center: www.healingwell.com/arthritis
Bone & Joint Decade (2002-USA-2011): www.boneandjointdecade.org/usa
National Institute of Arthritis and Musculoskeletal and Skin Diseases: www.niams.nih.gov/
Arthritis Information: www.arthritis.com
Arthritis news, information, & support: www.arthritis.about.com
All About Arthritis: www.allaboutarthritis.com
National Osteoporosis Foundation: http://www.nof.org/prevention/index.htm

 

Uses: Antibiotic that treats many different kinds of infections

Potential side effects: Diarrhea, nausea, skin rashes

Medications that may interact: Probenecid, allopurinol

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